| Versione (Motore) | Porte | Potenza (CV) | Tipo coupe | Posti | Inizio (anno) | Fine (anno) |
|---|---|---|---|---|---|---|
| 350 BlueTEC 3.0d (258hp) 4WD | 4 | 258 | Sedan | 4/5 | 2014 | 2018 |
| CLS 550 4.7 biturbo (408 Hp) | - | 408 | - | 4/5 | - | - |
| 550 4.7 (402hp) | 4 | 402 | Sedan | 4/5 | 2014 | 2017 |
| 220 BlueTEC 2.1d (170hp) | 4 | 204 | Sedan | 4/5 | 2014 | 2018 |
| 3.0 AT (435hp) 4x4 AMG | 4 | 435 | Sedan | 5 | 2021 | - |
| 350 BlueTEC 3.0d (258hp) | 4 | 259 | Sedan | 4/5 | 2014 | 2018 |
| 400 3.0 (333hp) 4WD | 4 | 265 | Sedan | 4/5 | 2014 | 2018 |
| 500 4.7 (408hp) | 4 | 408 | Sedan | 4/5 | 2014 | 2018 |
| 400 3.5 (333hp) 4WD | 4 | 333 | Sedan | 4/5 | 2014 | 2018 |
| 250 BlueTEC 2.1d (204hp) 4WD | 4 | 265 | Sedan | 4/5 | 2014 | 2018 |
| 250 BlueTEC 2.1d (204hp) | 4 | 265 | Sedan | 4/5 | 2014 | 2018 |
| 500 4.7 (408hp) 4WD | 4 | 408 | Sedan | 4/5 | 2014 | 2018 |
| 350 BlueTEC 3.0d (249hp) 4WD | 4 | 249 | Sedan | 4/5 | 2014 | 2018 |
| 400 3.5 (333hp) | 4 | 333 | Sedan | 4/5 | 2014 | 2018 |
| 550 4.7 (402hp) 4WD | 4 | 402 | Sedan | 4/5 | 2014 | 2018 |
| CLS 350 CDI BlueEFFICIENCY (261 Hp) | 4 | 261 | Coupe | 5 | 2011 | 2014 |
| 3.0 AT (435hp) 4x4 AMG | 4 | 435 | Sedan | 4/5 | 2018 | 2021 |
| CLS 350 BlueEFFICIENCY (302 Hp) | 4 | 302 | Coupe | 5 | 2011 | 2014 |
| CLS 250 CDI BlueEFFICIENCY (201 Hp) | 4 | 201 | Coupe | 5 | 2011 | 2014 |